Lumivive Wellness GLP-1 Program

Melanotan-1

Melanotan-1, also designated MT-1, afamelanotide, or [Nle4, D-Phe7]-alpha-MSH, is a synthetic linear analog of alpha-melanocyte-stimulating hormone (alpha-MSH). In laboratory research, Melanotan-1 is studied as a selective melanocortin-1 receptor (MC1R) agonist and as a tool compound for investigating the melanogenesis pathway and melanocortin-receptor signaling. Unlike the non-selective analog Melanotan-2, which engages multiple melanocortin receptors (MC1R through MC5R), the MT-1 research profile is weighted toward MC1R, the receptor most associated with melanin-synthesis pathways in preclinical models. Preclinical investigations have explored Melanotan-1 in experimental models studying: MC1R receptor binding and selectivity melanogenesis and melanin-synthesis pathways melanocyte signaling and gene-expression models photoprotection and UV-response research models melanocortin-receptor pharmacology and structure-activity relationships Mechanistic Research Insights Experimental research examines Melanotan-1 as an MC1R-selective melanocortin agonist, with downstream signaling studied primarily through the cyclic AMP (cAMP) pathway. Areas of investigation include: MC1R activation and cAMP signaling tyrosinase and melanin-synthesis enzyme pathways eumelanin production in melanocyte models receptor selectivity relative to MC3R, MC4R, and MC5R structure-activity relationships among alpha-MSH analogs These mechanisms are commonly studied in melanocyte cell cultures and receptor-binding assays. Compound Information Compound Name: Melanotan-1 (MT-1)Alternate Designations: Afamelanotide, [Nle4, D-Phe7]-alpha-MSH, NDP-MSHPeptide Class: Synthetic alpha-MSH Analog (Melanocortin Agonist)Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2Molecular Formula: C78H111N21O19Molecular Weight: ~1646.9 g/molCAS Number: 75921-69-6 Product Specifications Purity: ≥99%Testing Methods: HPLC & Mass SpectrometryAppearance: Lyophilized white powderCAS Number: 75921-69-6 Each batch undergoes analytical verification to confirm peptide identity, purity, and consistency. Storage For optimal stability, store lyophilized peptides in a cool, dry environment away from direct light. Long-term storage conditions may vary depending on laboratory requirements. Research Use Notice This compound is supplied strictly for laboratory research purposes only. Not intended for human consumption, therapeutic use, cosmetic use, or veterinary use.

$40.00