Clinical tool · Dosing
GLP-1 dose calculator
Convert a semaglutide or tirzepatide dose in milligrams to units on a standard U-100 insulin syringe, and review the reference weekly titration schedules.
Draw on a U-100 syringe
10units
= 0.1 mL of semaglutide at 2.5 mg/mL
Important
Units measure volume on a syringe, not a standardized drug amount — the same number of units is a different dose at a different concentration. Always confirm the labeled concentration on your vial and your syringe type before drawing. This tool does not replace guidance from a licensed provider and is not a prescription. Research compounds sold by Lumivive Wellness are for laboratory research use only.
Reference titration
Semaglutide weekly schedule
Half-life ≈ 7 days
- Weeks 1–4
- 0.25 mg weekly
- Weeks 5–8
- 0.5 mg weekly
- Weeks 9–12
- 1.0 mg weekly
- Weeks 13–16
- 1.7 mg weekly
- Weeks 17+
- 2.4 mg weekly (maintenance)
Reference titration
Tirzepatide weekly schedule
Half-life ≈ 5 days
- Weeks 1–4
- 2.5 mg weekly
- Weeks 5–8
- 5 mg weekly
- Weeks 9–12
- 7.5 mg weekly
- Weeks 13–16
- 10 mg weekly
- Weeks 17–20
- 12.5 mg weekly
- Weeks 21+
- 15 mg weekly (maximum)
Schedules above reflect the escalation patterns commonly cited in published GLP-1 literature. Many people hold a lower dose longer when appetite control is already effective or while side effects settle. Any change to a dosing plan should be made with a licensed provider.