{"product_id":"retatrutide","title":"Reta","description":"\u003cdiv class=\"elementor-element elementor-element-9c654e8 elementor-widget elementor-widget-woocommerce-product-title elementor-page-title elementor-widget-heading\" data-id=\"9c654e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"woocommerce-product-title.default\"\u003e\n\u003cdiv class=\"elementor-widget-container\"\u003e\n\u003ch2 class=\"product_title entry-title elementor-heading-title elementor-size-default\"\u003eReta\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"elementor-element elementor-element-c77382a elementor-widget elementor-widget-woocommerce-product-short-description\" data-id=\"c77382a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"woocommerce-product-short-description.default\"\u003e\n\u003cdiv class=\"elementor-widget-container\"\u003e\n\u003cdiv class=\"woocommerce-product-details__short-description\"\u003e\n\u003cp\u003eReta Research Grade (RUO) (CAS 2381089-83-2, LY3437943) is a 39–amino acid unimolecular peptide designed as a triple agonist for GIP \/ GLP-1 \/ Glucagon (GCG) receptors. Supplied as a lyophilized white powder with ≥99% purity (HPLC verified) and endotoxin \u0026lt;1.0 EU\/mg, it is soluble in sterile or bacteriostatic water.\u003c\/p\u003e\n\u003cp\u003eThe molecule includes a C20 fatty diacid moiety for albumin binding and extended stability (reported ~6-day half-life), supporting metabolic, obesity, T2D, and hepatic defatting research models.\u003cbr data-start=\"619\" data-end=\"622\"\u003eFor Research Use Only (RUO). Not for human or veterinary use.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch1\u003eReta (RUO) | Triple GIP\/GLP-1\/Glucagon Agonist | ≥99% Purity\u003c\/h1\u003e\n\u003ch2 class=\"wp-block-heading\"\u003eProduct Specifications\u003c\/h2\u003e\n\u003cul class=\"wp-block-list\"\u003e\n\u003cli\u003eProduct Name : Reta (Research Grade)\u003c\/li\u003e\n\u003cli\u003eCAS Number : 2381089-83-2\u003c\/li\u003e\n\u003cli\u003eCommon Name : LY3437943\u003c\/li\u003e\n\u003cli\u003eMolecular Formula : C221H342N46O68\u003c\/li\u003e\n\u003cli\u003eMolecular Weight : 4731 g\/mol\u003c\/li\u003e\n\u003cli\u003ePeptide Type : Triple-Hormone Receptor Agonist\u003c\/li\u003e\n\u003cli\u003eTarget Receptors : GIP \/ GLP-1 \/ Glucagon (GCG)\u003c\/li\u003e\n\u003cli\u003ePurity : ≥99% (HPLC Verified)\u003c\/li\u003e\n\u003cli\u003eForm : Lyophilized White Powder\u003c\/li\u003e\n\u003cli\u003eSolubility : Soluble in sterile water or bacteriostatic water\u003c\/li\u003e\n\u003cli\u003eEndotoxin Level : Less than 1.0 EU\/mg\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer : \u003c\/strong\u003eFor Research Use Only (RUO). Not for human use.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"wp-block-heading\"\u003eChemical Identity \u0026amp; Structural Mechanism\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp class=\"wp-block-paragraph\"\u003eReta is a synthetic unimolecular peptide comprising 39 amino acids. Unlike dual agonists, it integrates activity at the Glucagon Receptor (GCGR) alongside GIP and GLP-1, creating a “Triple Synergy”.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp class=\"wp-block-paragraph\"\u003eStructure-Activity Relationship (SAR): The backbone is derived from GIP but modified to introduce Glucagon activity. It features a C20 fatty diacid moiety that binds to albumin, protecting the peptide from enzymatic degradation and extending its half-life to approximately 6 days.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp class=\"wp-block-paragraph\"\u003eTuned Potency: Reta is designed with a specific hierarchy of potency: highest at GIP (for lipid buffering), moderate at GLP-1 (for satiety), and carefully tuned at Glucagon (to drive energy expenditure without hyperglycemia) .\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"wp-block-heading\"\u003eChemical structure of Reta (LY3437943)\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cimg data-attachment-id=\"91700\" data-permalink=\"https:\/\/profoundaminos.com\/?attachment_id=91700\" data-orig-file=\"https:\/\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure.webp\" data-orig-size=\"1500,1500\" data-comments-opened=\"1\" data-image-meta='{\"aperture\":\"0\",\"credit\":\"\",\"camera\":\"\",\"caption\":\"\",\"created_timestamp\":\"0\",\"copyright\":\"\",\"focal_length\":\"0\",\"iso\":\"0\",\"shutter_speed\":\"0\",\"title\":\"\",\"orientation\":\"0\"}' data-image-title=\"Retatrutide (LY3437943) 2D Molecular Structure\" data-image-description=\"\u0026lt;p\u0026gt;A simplified 2D chemical structure visualization of Retatrutide (LY3437943) displayed as a peptide-like chain with numerous functional groups and side chains. The graphic is used for compound identification and reference in research documentation related to GIP\/GLP-1\/glucagon receptor triple agonist studies (RUO).\u0026lt;\/p\u0026gt;\n\" data-image-caption=\"\u0026lt;p\u0026gt;2D structural diagram of Retatrutide (LY3437943), a research-grade triple agonist peptide.\u0026lt;\/p\u0026gt;\n\" data-large-file=\"https:\/\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-1024x1024.webp\" alt=\"2D molecular structure diagram of Retatrutide (LY3437943), a peptide-based triple agonist, showing the backbone chain with multiple side groups.\" width=\"300\" height=\"300\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" nitro-lazy-srcset=\"https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-300x300.webp 300w, 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https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-500x500.webp 500w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-100x100.webp 100w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure.webp 1500w\" nitro-lazy-src=\"https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-300x300.webp\" class=\"size-medium wp-image-91700 lazyloaded\" decoding=\"async\" nitro-lazy-empty=\"\" id=\"MjU1ODoxNDU5-1\" data-nitro-empty-id=\"MjU1ODoxNDU5-1\" src=\"https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-300x300.webp\" srcset=\"https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-300x300.webp 300w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-1024x1024.webp 1024w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-150x150.webp 150w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-768x768.webp 768w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-700x700.webp 700w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-500x500.webp 500w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure-100x100.webp 100w, https:\/\/cdn-iledacd.nitrocdn.com\/SjFAtUDKoxpKJBWpudFZVunbmeIDeGio\/assets\/images\/optimized\/rev-035c829\/profoundaminos.com\/wp-content\/uploads\/2024\/10\/Retatrutide-LY3437943-2D-Molecular-Structure.webp 1500w\"\u003e\u003c\/p\u003e\n\u003cp\u003ea triple-hormone receptor agonist (GIP\/GLP-1\/Glucagon). The highlighted C20 fatty acid moiety facilitates albumin binding, extending the half-life to ~6 days for sustained metabolic research.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Lumivive Wellness","offers":[{"title":"10MG","offer_id":52415346278680,"sku":null,"price":150.0,"currency_code":"USD","in_stock":true},{"title":"20MG","offer_id":52415346311448,"sku":null,"price":200.0,"currency_code":"USD","in_stock":true},{"title":"30MG","offer_id":52415346344216,"sku":null,"price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0988\/6177\/7176\/files\/40F9A815-E3E6-45F7-A3FE-AA9BBE939C62.png?v=1784396865","url":"https:\/\/lumivivewellness.com\/products\/retatrutide","provider":"Lumivive Wellness","version":"1.0","type":"link"}